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KMID : 0191120120270101261
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Journal of Korean Medical Science
2012 Volume.27 No. 10 p.1261 ~ p.1264
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Successful Treatment of Chronic Eosinophilic Pneumonia with Anti-IgE Therapy
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Shin Yoo-Seob
Jin Hyun-Jung
Yoo Hye-Soo
Hwang Eui-Kyung
Nam Young-Hee
Ye Young-Min
Park Hae-Sim
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Abstract
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Anti-IgE therapy, using recombinant humanized anti-IgE antibodies, is clinically effective in patients with eosinophil-related disorders such as allergic asthma, allergic rhinitis, and chronic urticaria. Chronic eosinophilic pneumonia tends to respond promptly to systemic corticosteroid therapy, however; relapses are common following corticosteroid tapering. We treated two patients (17- and 19-yr-old males) of chronic eosinophilic pneumonia whose symptoms were cough and dyspnea on exertion. The symptoms were recurrent while tapering off corticosteroid. They were treated with anti-IgE antibody without recurrence for 2 yr and 15 months. Here, we first describe clinical experience of the 2 cases of chronic eosinophilic pneumonia.
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KEYWORD
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Chronic Eosinophilic Pneumonia, Anti-IgE Therapy
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